Brain tumors are all diseases connected with benign and malignant brain neoplasms. Glioblastomas and brain metastases are two special disease forms.
Glioblastomas represent malignant brain tumors, which are primarily diagnosed in middle-aged and elderly people and are characterized by rapid progression. Glioblastomas are very treatment-resistant due to their rapid growth rates and surrounding brain tissues involvement. Therefore, in most cases such patients have unfavorable prognosis. That is why symptomatic relief is vitally essential in the treatment of the disease.
Brain metastases are secondary tumors, which develop in the other parts of the body, such as lungs or breast. Individual malignant cells may detach from the primary tumor and travel to the brain, where they reattach and continue to grow. Very often brain metastases determine the state of the disease thus representing one of the therapeutic objectives.
Brain tumors symptoms may vary greatly depending on the tumor type and localization. Nonspecific symptoms such as headache, nausea, and vomiting or convulsions may be primary sings of the disease. Speech and vision disorders may also be present. Different symptoms may manifest separately or in a complex and may intensify with tumor progression.
Interdisciplinary Therapy Based on Most Recent Scientific Progress
Brain tumor treatment may vary due to a certain type of the disease and patient condition. Treatment options include: surgery, X-ray therapy, chemotherapy or immunotherapy. These methods are used in a combination to achieve better results for a patient.
Due to complex biological characteristics of the disease, the requirements for brain tumor treatment are very strict. In the Center for Integrated Oncology of the University Clinic of Cologne specialists from different medical disciplines cooperate to achieve better results: interdisciplinary neurosurgeons, neurologists, and radiotherapists teams develop individual treatment concepts with subsequent certain disease target therapy implementation. The Center for Integrated Oncology offers patients new diagnostic and treatment methods, such as state-of-the-art X-ray therapy methods, fluorescence-guided resection of tumors, CyberKnife Surgery, and individualized chemotherapy.
Neuro-Oncology Studies in the Center for Integrated Oncology of the University Clinic of Cologne
To optimize brain tumors treatment and prognosis the Center for Integrated Oncology participate in all German and international large-scale studies of malignant brain tumors thus promoting scientific progress in the sphere. Achievements of the Center for Integrated Oncology Köln Bonn stuff have provided a basis for new clinical studies.
In cooperation with Max Planck Institute and other Research Centers and University Clinic Departments of Germany the Center for Integrated Oncology also develops new diagnostic and visualization methods involving innovative MRI sequences and positron emission tomography (PET). For example, new diagnostic methods such as synchronous visualization using MRI and PET hybrid are studied and applied in cooperation with Jülich Research Centre. Study results obtained by the Center for Integrated Oncology in relation to brain tumors PET diagnostics and stereotactic therapy have already gained worldwide recognition and are used in other countries. We focus on continuous development of new standards for oncologic treatment.